SCHEMBL24601870

SCHEMBL24601870

Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2CO[P@@](=O)(S)O[C@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3CO[PH](=O)O[C@@H]1[C@@H]2O

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21118440 1.00 STING1 (0.64) STING1
SCHEMBL23635842 1.00 STING1 (0.64) STING1
SCHEMBL18937434 0.91 STING1 (0.77) STING1
SCHEMBL23477356 0.91 STING1 (0.77) STING1
SCHEMBL25854717 0.90 STING1 (0.75) STING1
SCHEMBL18822959 0.90 STING1 (0.75) STING1
SCHEMBL23476968 0.89 STING1 (0.65) STING1
SCHEMBL23477418 0.89 STING1 (0.65) STING1
SCHEMBL23799805 0.89 STING1 (0.56) STING1
SCHEMBL23618667 0.88 STING1 (0.75) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220211815-A1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER CHINOOK THERAPEUTICS, INC. 2022-07-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211815-A1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER STING1, IL15RA, IL15 STING1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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