Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21160841 | 0.75 | CYP1A2 (0.71) | CYP1A2MAPTKDM4ECYP3A4CYP2D6 | |
| SCHEMBL21865868 | 0.74 | CYP1A2 (0.55) | CYP1A2MAPTCYP3A4CYP2D6HIF1A | |
| SCHEMBL12451410 | 0.73 | CYP1A2 (0.51) | CYP1A2MAPTKDM4ECYP3A4CYP2D6 | |
| SCHEMBL15827402 | 0.72 | KDM4E (0.58) | CYP1A2MAPTKDM4ETDP1 | |
| SCHEMBL94770 | 0.71 | MAPT (0.50) | MAPTKDM4ECYP2D6OPRM1OPRK1 | |
| SCHEMBL10311141 | 0.71 | KDM4E (0.43) | CYP1A2MAPTKDM4ETDP1 | |
| SCHEMBL18134602 | 0.71 | CYP1A2 (1.00) | CYP1A2MAPTKDM4ECYP3A4CYP2D6 | |
| SCHEMBL28677044 | 0.70 | CYP1A2 (0.62) | CYP1A2MAPTCYP3A4CYP2D6HIF1A | |
| SCHEMBL15892647 | 0.70 | KDM4E (0.39) | CYP1A2MAPTKDM4ECYP3A4 | |
| SCHEMBL10311142 | 0.69 | CYP1A2 (0.49) | CYP1A2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213267-A1 | EXTREME HIGH TEMPERATURE STABLE ADHESIVES AND COATINGS | DESIGNER MOLECULES, INC | 2022-07-07 | — | — | US | disclosed |