Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2463576 | 0.98 | IGF1R (0.87) | IGF1R | |
| SCHEMBL2457626 | 0.94 | IGF1R (0.81) | IGF1R | |
| SCHEMBL2461454 | 0.93 | IGF1R (1.00) | IGF1R | |
| SCHEMBL12335692 | 0.91 | IGF1R (0.81) | IGF1R | |
| SCHEMBL2461516 | 0.91 | IGF1R (0.81) | IGF1R | |
| SCHEMBL12335697 | 0.90 | IGF1R (0.80) | IGF1R | |
| SCHEMBL2463118 | 0.90 | IGF1R (0.80) | IGF1R | |
| Carbamic Acid SCHEMBL2460202 | 0.89 | IGF1R (0.92) | IGF1R | |
| SCHEMBL2463511 | 0.87 | IGF1R (1.00) | IGF1R | |
| SCHEMBL2459463 | 0.87 | IGF1R (0.88) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675860-B1 | IMIDAZO[1,5-A]PYRAZINES AS TYROSINE KINASE INHIBITORS | OSI PHARM INC (US) | 2011-09-21 | — | — | EP | claimed |