Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18074011 | 0.83 | PIK3CD (0.45) | PIK3CDHRH3KDM4EPOLB | |
| SCHEMBL9976596 | 0.83 | PIK3CD (0.45) | PIK3CDHRH3KDM4EPOLB | |
| SCHEMBL18663983 | 0.75 | PIK3CD (0.45) | PIK3CDHRH3KDM4EPOLB | |
| SCHEMBL18664002 | 0.75 | PIK3CD (0.45) | PIK3CDHRH3KDM4EPOLB | |
| SCHEMBL18664096 | 0.75 | PIK3CD (0.45) | PIK3CDHRH3KDM4EPOLB | |
| SCHEMBL23945597 | 0.75 | PIK3CD (0.41) | PIK3CDHRH3KDM4E | |
| SCHEMBL6124875 | 0.74 | PIK3CD (0.43) | PIK3CDHRH3KDM4E | |
| SCHEMBL20093334 | 0.74 | SMN1; SMN2 (0.42) | HRH3KDM4E | |
| SCHEMBL19501163 | 0.73 | PIK3CD (0.44) | PIK3CDHRH3POLB | |
| SCHEMBL18664005 | 0.73 | PIK3CD (0.44) | PIK3CDHRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |