Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29751167 | 1.00 | IRAK4 (0.69) | IRAK4 | |
| SCHEMBL24607174 | 0.94 | IRAK4 (0.69) | IRAK4 | |
| SCHEMBL24607175 | 0.94 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL29751651 | 0.92 | IRAK4 (0.68) | IRAK4 | |
| SCHEMBL24607389 | 0.92 | IRAK4 (0.68) | IRAK4 | |
| SCHEMBL29709746 | 0.91 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL24508743 | 0.91 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL29751255 | 0.87 | IRAK4 (0.65) | IRAK4 | |
| SCHEMBL24607319 | 0.87 | IRAK4 (0.65) | IRAK4 | |
| SCHEMBL21949093 | 0.84 | IRAK4 (0.89) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |