Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29751427 | 1.00 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL24607164 | 0.91 | IRAK4 (0.70) | IRAK4 | |
| SCHEMBL24607166 | 0.91 | IRAK4 (0.69) | IRAK4 | |
| SCHEMBL24607589 | 0.90 | IRAK4 (0.62) | IRAK4 | |
| SCHEMBL29751296 | 0.90 | IRAK4 (0.62) | IRAK4 | |
| SCHEMBL29751464 | 0.89 | IRAK4 (0.69) | IRAK4 | |
| SCHEMBL24608427 | 0.89 | IRAK4 (0.69) | IRAK4 | |
| SCHEMBL29709746 | 0.88 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL24508743 | 0.88 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL16873596 | 0.83 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |