Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.32 |
| ▸ | CA2 | P00918 | 6/20 | 0.32 |
| ▸ | CA12 | O43570 | 5/20 | 0.32 |
| ▸ | CA9 | Q16790 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23077453 | 0.89 | STING1 (0.40) | STING1CYP3A4CA1CA2CA12 | |
| SCHEMBL22121412 | 0.88 | STING1 (0.38) | STING1CYP3A4CA1CA2CA12 | |
| SCHEMBL29436988 | 0.85 | STING1 (0.37) | STING1CYP3A4 | |
| SCHEMBL23095351 | 0.85 | STING1 (0.37) | STING1CYP3A4 | |
| SCHEMBL31016354 | 0.84 | STING1 (0.36) | STING1CYP3A4 | |
| SCHEMBL29012734 | 0.83 | STING1 (0.45) | STING1CYP3A4 | |
| SCHEMBL20889072 | 0.83 | STING1 (0.45) | STING1CYP3A4 | |
| SCHEMBL29406354 | 0.83 | STING1 (0.45) | STING1CYP3A4 | |
| SCHEMBL25098877 | 0.83 | STING1 (0.46) | STING1CYP3A4CA1CA2CA12 | |
| SCHEMBL29868394 | 0.83 | STING1 (0.46) | STING1CYP3A4CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802534-B1 | TRICYCLIC HETEROCYCLIC COMPOUNDS AS STING ACTIVATORS | INCYTE CORP (US) | 2022-07-13 | — | — | EP | disclosed |