Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23949024 | 1.00 | CD274 (0.64) | CD274PDCD1 | |
| SCHEMBL23961513 | 0.95 | CD274 (0.59) | CD274PDCD1 | |
| SCHEMBL23949463 | 0.95 | CD274 (0.59) | CD274PDCD1 | |
| SCHEMBL23961528 | 0.93 | CD274 (0.60) | CD274PDCD1 | |
| SCHEMBL23948887 | 0.93 | CD274 (0.60) | CD274PDCD1 | |
| SCHEMBL23961487 | 0.92 | PDCD1 (0.63) | CD274PDCD1 | |
| SCHEMBL23961419 | 0.88 | PDCD1 (0.71) | CD274PDCD1 | |
| SCHEMBL23948990 | 0.88 | PDCD1 (0.75) | CD274PDCD1 | |
| SCHEMBL23949464 | 0.88 | PDCD1 (0.75) | CD274PDCD1 | |
| SCHEMBL23949023 | 0.87 | CD274 (0.66) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |