Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.55 |
| ▸ | PDCD1LG2 | Q9BQ51 | 19/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24613043 | 0.93 | CD274 (0.49) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23948921 | 0.90 | CD274 (0.55) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23949330 | 0.84 | CD274 (0.51) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24613510 | 0.83 | CD274 (0.50) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24613139 | 0.82 | CD274 (0.48) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23948967 | 0.81 | PDCD1 (0.45) | CD274PDCD1 | |
| SCHEMBL23948928 | 0.81 | CD274 (0.49) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23949426 | 0.81 | CD274 (0.49) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24613689 | 0.78 | CD274 (0.47) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23949324 | 0.77 | PDCD1 (0.49) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |