Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.64 |
| ▸ | PDCD1 | Q15116 | 16/20 | 0.64 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24613700 | 0.94 | CD274 (0.57) | CD274PDCD1S1PR4 | |
| SCHEMBL24613304 | 0.91 | CD274 (0.64) | CD274PDCD1 | |
| SCHEMBL22867300 | 0.84 | CD274 (0.74) | CD274PDCD1 | |
| SCHEMBL23948831 | 0.83 | CD274 (0.83) | CD274PDCD1 | |
| SCHEMBL29964955 | 0.82 | CD274 (0.60) | CD274 | |
| SCHEMBL22820882 | 0.82 | CD274 (0.60) | CD274 | |
| SCHEMBL23949384 | 0.81 | CD274 (0.74) | CD274PDCD1 | |
| SCHEMBL29724510 | 0.81 | CD274 (0.74) | CD274PDCD1 | |
| SCHEMBL22866949 | 0.79 | CD274 (0.59) | CD274PDCD1 | |
| SCHEMBL24613260 | 0.77 | CD274 (0.59) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |