Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 7/20 | 0.32 |
| ▸ | AXL | P30530 | 4/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467694 | 0.92 | CHRM1 (0.35) | CHRM1METAXLCLK1RAB9A | |
| SCHEMBL2458317 | 0.90 | CHRM1 (0.39) | CHRM1METAXLCLK1RAB9A | |
| SCHEMBL2461831 | 0.89 | CHRM1 (0.39) | CHRM1METAXLCLK1RAB9A | |
| SCHEMBL2462952 | 0.86 | CHRM1 (0.37) | CHRM1METAXLCLK1RAB9A | |
| SCHEMBL12160648 | 0.86 | CHRM1 (0.35) | CHRM1METAXLCLK1RAB9A | |
| SCHEMBL2488754 | 0.85 | CHRM1 (0.37) | CHRM1METCLK1RAB9AMAOB | |
| Potassium Ion SCHEMBL2491473 | 0.85 | CHRM1 (0.37) | CHRM1METCLK1RAB9AMAOB | |
| SCHEMBL2464053 | 0.85 | CHRM1 (0.37) | CHRM1METCLK1RAB9AMAOB | |
| SCHEMBL17970297 | 0.85 | CHRM1 (0.33) | CHRM1METAXLCLK1RAB9A | |
| SCHEMBL2464324 | 0.85 | FFAR1 (0.33) | METAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010064735-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |