Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.63 |
| ▸ | PDCD1 | Q15116 | 18/20 | 0.63 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24613631 | 1.00 | CD274 (0.63) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL24613783 | 0.91 | PDCD1 (0.55) | CD274PDCD1 | |
| SCHEMBL24613447 | 0.86 | CD274 (0.64) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23949757 | 0.86 | CD274 (0.64) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23948879 | 0.86 | CD274 (0.64) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23961526 | 0.84 | PDCD1 (0.66) | CD274PDCD1 | |
| SCHEMBL20539289 | 0.84 | CD274 (0.60) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23949231 | 0.84 | CD274 (0.60) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23961477 | 0.83 | CD274 (0.63) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23961520 | 0.83 | CD274 (0.63) | CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |