Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23948746 | 1.00 | CD274 (0.66) | CD274PDCD1 | |
| SCHEMBL20539413 | 1.00 | CD274 (0.66) | CD274PDCD1 | |
| SCHEMBL23948940 | 0.96 | CD274 (0.62) | CD274PDCD1 | |
| SCHEMBL24613409 | 0.94 | CD274 (0.59) | CD274PDCD1 | |
| SCHEMBL20539841 | 0.86 | CD274 (0.58) | CD274PDCD1 | |
| SCHEMBL23949243 | 0.86 | CD274 (0.58) | CD274PDCD1 | |
| SCHEMBL20539714 | 0.85 | PDCD1 (0.47) | CD274PDCD1 | |
| SCHEMBL23948935 | 0.83 | CD274 (0.60) | CD274PDCD1 | |
| SCHEMBL23948982 | 0.83 | CD274 (0.60) | CD274PDCD1 | |
| SCHEMBL20539430 | 0.83 | CD274 (0.60) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |