Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SIK1 | P57059 | 2/20 | 0.50 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.50 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17152727 | 0.85 | HPGD (0.54) | HPGDSIK1SIK2SIK3FGFR1 | |
| SCHEMBL24614566 | 0.85 | SIK1 (0.53) | HPGDSIK1SIK2SIK3FGFR1 | |
| SCHEMBL24614567 | 0.80 | FGFR1 (0.68) | HPGDSIK1SIK2SIK3FGFR1 | |
| SCHEMBL29776603 | 0.77 | SIK1 (0.52) | HPGDSIK1SIK2SIK3FGFR1 | |
| SCHEMBL28577316 | 0.77 | SIK1 (0.52) | HPGDSIK1SIK2SIK3FGFR1 | |
| SCHEMBL31036602 | 0.76 | FGFR1 (0.66) | FGFR1ALDH1A1KDR | |
| SCHEMBL1129240 | 0.76 | FGFR1 (0.66) | FGFR1ALDH1A1KDR | |
| SCHEMBL121458 | 0.75 | FGFR1 (0.72) | HPGDFGFR1THRBALDH1A1GSK3B | |
| SCHEMBL2666380 | 0.75 | HPGD (0.52) | HPGDFGFR1ALDH1A1AURKAKDR | |
| SCHEMBL14065338 | 0.75 | FGFR1 (0.76) | HPGDSIK1SIK2SIK3FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148196-A1 | MULTIKINASE INHIBITOR AND USE THEREOF | 苏州安睿药业有限公司 | 2022-07-14 | — | — | WO | disclosed |