Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.46 |
| ▸ | JAK1 | P23458 | 17/20 | 0.44 |
| ▸ | JAK2 | O60674 | 15/20 | 0.43 |
| ▸ | TYK2 | P29597 | 15/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 5/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669773 | 1.00 | RET (0.46) | RETJAK1JAK2TYK2GPR119 | |
| SCHEMBL30726637 | 0.90 | RET (0.42) | RETJAK1JAK2TYK2GPR119 | |
| SCHEMBL29772835 | 0.87 | JAK2 (0.57) | JAK1JAK2TYK2JAK3KDR | |
| SCHEMBL29772826 | 0.87 | JAK2 (0.57) | JAK1JAK2TYK2JAK3KDR | |
| SCHEMBL24615462 | 0.87 | JAK2 (0.57) | JAK1JAK2TYK2JAK3KDR | |
| SCHEMBL24615242 | 0.86 | JAK2 (0.42) | JAK1JAK2TYK2JAK3KDR | |
| SCHEMBL24615445 | 0.84 | JAK1 (0.60) | JAK1JAK2TYK2JAK3KDR | |
| SCHEMBL24615446 | 0.84 | JAK1 (0.60) | JAK1JAK2TYK2JAK3KDR | |
| SCHEMBL29772810 | 0.84 | JAK1 (0.46) | RETJAK1JAK2TYK2GPR119 | |
| SCHEMBL29772763 | 0.84 | JAK1 (0.60) | JAK1JAK2TYK2JAK3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547674-A1 | TYK2 INHIBITORS | Biogen MA Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119731186-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024006493-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| CN-117098763-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| EP-4274832-A1 | TYK2 INHIBITORS | Biogen MA Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |