SCHEMBL24615399

SCHEMBL24615399

O=C(C1CC1)N1C2CCC1CN(c1ncnn3cc(-c4cnn(C(F)F)c4)cc13)C2

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24615319 0.92 KIT (0.51) KIT
SCHEMBL24615585 0.91 KIT (0.52) KIT
SCHEMBL29772715 0.91 KIT (0.50) KIT
SCHEMBL24615394 0.91 KIT (0.61) KIT
SCHEMBL24615300 0.90 KIT (0.49) KIT
SCHEMBL24615562 0.90 KIT (0.48) KIT
SCHEMBL24615561 0.90 KIT (0.48) KIT
SCHEMBL24615343 0.90 KIT (0.49) KIT
SCHEMBL24615577 0.90 KIT (0.50) KIT
SCHEMBL24615315 0.90 KIT (0.48) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022150446-A1 TYK2 INHIBITORS BIOGEN MA INC. (US) 2022-07-14 WO disclosed