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SCHEMBL24616667

SCHEMBL24616667

CCCC(NC(=O)C(CS)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(CCCCN)NC(=O)C(N)Cc1c[nH]cn1)C(=O)NC(C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SLC15A2 Q16348 1/20 0.38
▸ PDF Q9HBH1 1/20 0.35
▸ GHSR Q92847 3/20 0.35
▸ CCNA2 P20248 2/20 0.34
▸ CDK2 P24941 2/20 0.34
▸ CCNA1 P78396 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24616668 1.00 SLC15A2 (0.38) SLC15A2PDFGHSRCCNA2CDK2
SCHEMBL30618482 0.90 SLC15A2 (0.42) SLC15A2GHSRCCNA2CDK2CCNA1
SCHEMBL31188431 0.87 SLC15A2 (0.42) SLC15A2GHSR
SCHEMBL30762202 0.87 SLC15A2 (0.44) SLC15A2PDFGHSR
SCHEMBL31041774 0.86 CALCR (0.38) SLC15A2
SCHEMBL31385114 0.85 SLC15A2 (0.41) SLC15A2GHSR
SCHEMBL14332340 0.85 SLC15A2 (0.48) SLC15A2GHSR
SCHEMBL14332343 0.85 SLC15A2 (0.48) SLC15A2GHSR
SCHEMBL29484176 0.84 SLC15A2 (0.48) SLC15A2
SCHEMBL29942276 0.84 SLC15A2 (0.48) SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022150508-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF PCSK9 SIRNAOMICS, INC. (US) 2022-07-14 — — WO disclosed
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