SCHEMBL2461897

SCHEMBL2461897

CCCCCCC[C@H]1CC[C@H](c2ccc(C#N)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.45
SPHK1 Q9NYA1 8/20 0.44
GRM2 Q14416 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP2C9 P11712 1/20 0.43
MAPT P10636 2/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GAA P10253 1/20 0.41
ESR2 Q92731 1/20 0.40
SPHK2 Q9NRA0 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11615901 1.00 MEN1 (0.45) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL11617810 1.00 MEN1 (0.45) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL11614254 1.00 MEN1 (0.45) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL261098 1.00 MEN1 (0.45) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL11615960 1.00 MEN1 (0.45) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL9174057 1.00 MEN1 (0.45) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL9156790 1.00 MEN1 (0.45) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL11619542 1.00 MEN1 (0.45) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL9578194 0.98 MEN1 (0.46) MEN1KMT2AMAPK1SPHK1GRM2
SCHEMBL2370340 0.98 MEN1 (0.46) MEN1KMT2AMAPK1SPHK1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP claimed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP claimed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP claimed
US-4908152-A Cyclohexane derivative CHISSO CORPORATION (JP) 1990-03-13 US claimed
US-4733949-A LOW TEMPERATURE RESPONSE TIME HITACHI, LTD. (JP) 1988-03-29 US claimed
US-4695398-A Cyclohexane derivative CHISSO CORPORATION (JP) 1987-09-22 US claimed
US-4623477-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1986-11-18 US claimed
US-4548731-A LIQUID CRYSTALS DISPLAY ELEMENTS CHISSO CORPORATION (JP) 1985-10-22 US claimed
US-4272162-A Guest-host liquid crystal display device CITIZEN WATCH CO., LTD. (JP) 1981-06-09 US claimed
US-4228030-A Liquid crystal compositions GENERAL ELECTRIC COMPANY (US) 1980-10-14 US claimed
JP-56036566-A None JP disclosed
US-8330890-B2 Display device SHARP KABUSHIKI KAISHA (JP) 2012-12-11 US disclosed
US-8026992-B2 Display device SHARP KABUSHIKI KAISHA (JP) 2011-09-27 US disclosed
US-20100321600-A1 Display device SHARP KABUSHIKI KAISHA (JP) 2010-12-23 US disclosed
US-7768589-B2 Display device SHARP KABUSHIKI KAISHA (JP) 2010-08-03 US disclosed
US-4232949-A ANTHRAQUINONE DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-11-11 US disclosed
US-4232950-A ANTHRAQUINONE DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-11-11 US disclosed
US-4228030-A Liquid crystal compositions GENERAL ELECTRIC COMPANY (US) 1980-10-14 US disclosed
US-4196975-A Azine liquid crystal compounds for use in light-control devices GENERAL ELECTRIC COMPANY (US) 1980-04-08 US disclosed
US-4154697-A Liquid crystalline hexahydroterphenyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1979-05-15 US disclosed