SCHEMBL2461932

SCHEMBL2461932

CCOS(=O)(=O)CC(C)O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
TSHR P16473 1/20 0.35
MAPT P10636 1/20 0.31
TP53 P04637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27647832 0.83 CA1 (0.40) CA1CA2
SCHEMBL8396145 0.80 CA1 (0.42) CA1CA2CA9
SCHEMBL28649416 0.79 CA1 (0.47) CA1CA2TSHRMAPTTP53
SCHEMBL28751455 0.77 TDP1 (0.32)
SCHEMBL28705763 0.77 TSHR (0.33) TSHR
SCHEMBL28648470 0.77 CA1 (0.45) CA1CA2TSHRMAPTTP53
SCHEMBL22578299 0.76 CA1 (0.39) CA1CA2CA9
SCHEMBL20743495 0.76 MAPK1 (0.32)
SCHEMBL9859458 0.76 CA1 (0.34) CA1CA2CA9
SCHEMBL27745824 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012066366-A1 NEW SALTS SUITABLE FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS EGIS GYŐGYSZERGYÁR NYILVÁNOSAN MŰKÖDÖ RÉSZVÉNYTÁR-SASÁG (HU) 2012-05-24 WO disclosed
WO-2011110876-A1 NOVEL SALTS FOR THE MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MŰKÖDŐ RÉSZVÉNYTÁRSASÁG (HU) 2011-09-15 WO disclosed