Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30086158 | 1.00 | MAPT (0.77) | MAPTTHRBTP53LMNAALDH1A1 | |
| SCHEMBL24106017 | 0.91 | MAPT (0.85) | MAPTTHRBTP53LMNAALDH1A1 | |
| SCHEMBL30086019 | 0.91 | MAPT (0.85) | MAPTTHRBTP53LMNA | |
| SCHEMBL24105969 | 0.91 | MAPT (0.85) | MAPTTHRBTP53LMNA | |
| SCHEMBL29924996 | 0.91 | MAPT (0.78) | MAPTTHRBTP53LMNA | |
| SCHEMBL30086024 | 0.91 | MAPT (0.78) | MAPTTHRBTP53LMNA | |
| SCHEMBL24619261 | 0.91 | MAPT (0.84) | MAPTTHRBTP53LMNA | |
| SCHEMBL24619405 | 0.91 | MAPT (0.78) | MAPTTHRBTP53LMNA | |
| SCHEMBL24619411 | 0.91 | MAPT (0.78) | MAPTTHRBTP53LMNA | |
| SCHEMBL29924889 | 0.91 | MAPT (0.84) | MAPTTHRBTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010762-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| US-20220370431-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-11-24 | — | — | US | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220370431-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | MYC, MYCBP, MYCBP2 | MAPT 3215/4885THRB 2134/4885TP53 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.