Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 14/20 | 0.42 |
| ▸ | BCL2 | P10415 | 9/20 | 0.42 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26844943 | 0.89 | BCL2L1 (0.45) | BCL2L1BCL2NPC1RAB9AKDM4E | |
| SCHEMBL26657746 | 0.86 | BCL2L1 (0.56) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL26845024 | 0.86 | BCL2L1 (0.43) | BCL2L1BCL2NPC1RAB9A | |
| SCHEMBL24619868 | 0.83 | BCL2L1 (0.39) | BCL2L1BCL2BCL2L2FAAHKDM4E | |
| SCHEMBL24629034 | 0.83 | BCL2L1 (0.43) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL24619782 | 0.82 | BCL2L1 (0.40) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL26857118 | 0.77 | BCL2L1 (0.59) | BCL2L1BCL2 | |
| SCHEMBL26844962 | 0.77 | BCL2L1 (0.47) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL26680363 | 0.77 | BCL2L1 (0.60) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL26657560 | 0.75 | BCL2L1 (0.75) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |
| WO-2022149618-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |