Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930639 | 0.76 | USP2 (0.42) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| SCHEMBL10202118 | 0.73 | USP2 (0.40) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| SCHEMBL2683916 | 0.72 | USP2 (0.39) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| SCHEMBL15116477 | 0.72 | USP2 (0.39) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL10884122 | 0.70 | USP2 (0.38) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| SCHEMBL10202326 | 0.70 | USP2 (0.38) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| SCHEMBL4743121 | 0.70 | CYP1A2 (0.41) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| SCHEMBL4728514 | 0.70 | USP2 (0.38) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| SCHEMBL19388185 | 0.68 | USP2 (0.36) | MAPK1USP2JAK3CYP1A2CYP2C9 | |
| SCHEMBL15113633 | 0.68 | CYP1A2 (0.40) | MAPK1USP2JAK3CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218661-A1 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218661-A1 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | CBR3, C1R, CBR1 | MAPK1 4142/4885USP2 538/4885JAK3 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.