Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.71 |
| ▸ | TNKS | O95271 | 3/20 | 0.69 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923122 | 1.00 | PARP1 (0.71) | PARP1TNKSTNKS2 | |
| SCHEMBL29922956 | 1.00 | PARP1 (0.71) | PARP1TNKSTNKS2 | |
| SCHEMBL23113133 | 0.90 | PARP1 (0.65) | PARP1TNKSTNKS2 | |
| SCHEMBL29535734 | 0.89 | PARP1 (0.75) | PARP1TNKSTNKS2 | |
| SCHEMBL22656867 | 0.89 | PARP1 (0.75) | PARP1TNKSTNKS2 | |
| SCHEMBL28975588 | 0.89 | PARP1 (0.81) | PARP1TNKSTNKS2 | |
| SCHEMBL29923010 | 0.88 | PARP1 (0.76) | PARP1TNKSTNKS2 | |
| SCHEMBL29922994 | 0.88 | PARP1 (0.76) | PARP1TNKSTNKS2 | |
| SCHEMBL23113221 | 0.87 | PARP1 (0.75) | PARP1TNKSTNKS2 | |
| SCHEMBL30293105 | 0.87 | PARP1 (0.89) | PARP1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148822-A1 | USP5 BINDING SURVIVAL-TARGETING CHIMERIC (SURTAC) MOLECULES & USES THEREOF | LOCKI THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |