⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720595 | 0.93 | — | — | |
| SCHEMBL5263716 | 0.87 | — | — | |
| SCHEMBL4721677 | 0.84 | — | — | |
| SCHEMBL9255631 | 0.79 | EPHX1 (0.35) | — | |
| SCHEMBL28862775 | 0.77 | — | — | |
| SCHEMBL4720803 | 0.77 | — | — | |
| SCHEMBL20635059 | 0.77 | — | — | |
| SCHEMBL12881254 | 0.77 | — | — | |
| SCHEMBL68356 | 0.77 | EPHX1 (0.38) | — | |
| SCHEMBL9798578 | 0.77 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256299-A1 | 7-MORPHOLINO-5-(3-PHENYL-1 H-PYRAZOL-1 -YL)-FURO[3,2-B]PYRIDINE DERIVATIVES AND SIMILAR COMPOUNDS AS PIKFYVE KINASE INHIBITORS FOR THE TREATMENT OF E.G. AMYOTROPHIC LATERAL SCLEROSIS (ALS) | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | claimed |
| EP-3532898-A1 | METHOD FOR PRODUCING A POLYMER BY NITROXYL-CONTROLLED POLYMERISATION, AND POLYMER | Fraunhofer Gesellschaft zur Förderung der Angewand (DE) | 2019-09-04 | — | — | EP | claimed |
| CN-115028787-B | Polar modifier system for high vinyl block copolymerization | 戴纳索尔伊莱斯托米罗斯公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117821429-A | Recombinant protease mutant, coding gene, vector, engineering bacterium and application of recombinant protease mutant in resolution of (R, S) -2-tetrahydrofurfuryl acid ethyl ester | 浙江工业大学 | 2024-04-05 | — | — | CN | disclosed |
| US-20230094374-A1 | Polar Modifier Systems for High Vinyl Block Copolymerization | DYNASOL ELASTÓMEROS, S.A. DE C.V. (MX) | 2023-03-30 | — | — | US | disclosed |
| US-11542355-B2 | Polar modifier systems for high vinyl block copolymerization | DYNASOL ELASTÓMEROS, S.A. DE C.V. | 2023-01-03 | — | — | US | disclosed |
| WO-2022256299-A1 | 7-MORPHOLINO-5-(3-PHENYL-1 H-PYRAZOL-1 -YL)-FURO[3,2-B]PYRIDINE DERIVATIVES AND SIMILAR COMPOUNDS AS PIKFYVE KINASE INHIBITORS FOR THE TREATMENT OF E.G. AMYOTROPHIC LATERAL SCLEROSIS (ALS) | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022256300-A1 | FUSED BICYCLIC HETEROCYCLIC COMPOUNDS AND USES THEREOF | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | disclosed |
| CN-115028787-A | Polar modifier system for high vinyl block copolymerization | 戴纳索尔伊莱斯托米罗斯公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-109312037-B | Polar modifier system for high vinyl block copolymerization | 戴纳索尔伊莱斯托米罗斯公司 | 2022-07-29 | — | — | CN | disclosed |
| US-20210171696-A1 | Polar Modifier Systems for High Vinyl Block Copolymerization | DYNASOL ELASTÓMEROS, S.A. DE C.V. (MX) | 2021-06-10 | — | — | US | disclosed |
| US-5892042-A | OPTICAL RECORDING MEDIA WITH ACRIDINE DYES ON TRANSPARENT SUBSTRATE | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| US-5792863-A | HAVING LARGE ABSORPTION IN NEAR INFRARED, REDUCED ABSORPTION IN VISIBLE RANGE | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| CN-1189508-A | Anionic copolymerization of conjugated dienes and vinyl arenes in presence of alkyl ethers of tetrahydropyranyl methanol | ENICHEM SPA (IT) | 1998-08-05 | — | — | CN | disclosed |
| WO-1996000219-A1 | PYRIMIDINYL- AND TRIAZINYL-OXY AND THIO-3-HALOALKYL-PROPIONIC ACID DERIVATIVES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1996-01-04 | — | — | WO | disclosed |
| US-5455355-A | Postemergence, preemergence herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-03 | — | — | US | disclosed |
| US-5298632-A | Herbicidal pyrimidine compounds, compositions containing the same and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5232897-A | Herbicidal pyrimidine compounds, compositions containing the same and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0457505-A2 | Pyrimidine derivatives and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-21 | — | — | EP | disclosed |
| EP-0245209-A1 | Milbemycin derivatives, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1987-11-11 | — | — | EP | disclosed |