Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 10/20 | 0.83 |
| ▸ | KDR | P35968 | 8/20 | 0.83 |
| ▸ | TEK | Q02763 | 7/20 | 0.83 |
| ▸ | KIT | P10721 | 6/20 | 0.69 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.69 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.69 |
| ▸ | CSF1R | P07333 | 3/20 | 0.67 |
| ▸ | SRC | P12931 | 4/20 | 0.62 |
| ▸ | ABL1 | P00519 | 3/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.59 |
| ▸ | BCR | P11274 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | YES1 | P07947 | 1/20 | 0.56 |
| ▸ | LYN | P07948 | 1/20 | 0.56 |
| ▸ | HCK | P08631 | 1/20 | 0.56 |
| ▸ | FGR | P09769 | 1/20 | 0.56 |
| ▸ | CSK | P41240 | 1/20 | 0.56 |
| ▸ | BLK | P51451 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969534 | 0.91 | LCK (1.00) | LCKKDRTEKKITDDR1 | |
| SCHEMBL3430966 | 0.90 | LCK (0.75) | LCKKDRTEKKITDDR1 | |
| SCHEMBL2974278 | 0.89 | LCK (1.00) | LCKKDRTEKKITDDR1 | |
| SCHEMBL2975413 | 0.85 | LCK (1.00) | LCKKDRTEKKITDDR1 | |
| SCHEMBL14953284 | 0.85 | LCK (0.77) | LCKKDRTEKKITDDR1 | |
| SCHEMBL29515236 | 0.85 | LCK (0.77) | LCKKDRTEKKITDDR1 | |
| SCHEMBL3586277 | 0.84 | TEK (0.77) | LCKKDRTEKKITDDR1 | |
| SCHEMBL3574810 | 0.84 | LCK (1.00) | LCKKDRTEKKITDDR1 | |
| SCHEMBL2976092 | 0.83 | LCK (0.86) | LCKKDRTEKKITDDR1 | |
| SCHEMBL17325058 | 0.83 | LCK (0.73) | LCKKDRTEKKITDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |