⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2394984 | 1.00 | — | — | |
| SCHEMBL1068476 | 1.00 | — | — | |
| SCHEMBL4489033 | 0.78 | TDP1 (0.34) | — | |
| SCHEMBL4492370 | 0.74 | — | — | |
| SCHEMBL2256073 | 0.73 | — | — | |
| SCHEMBL584203 | 0.71 | — | — | |
| SCHEMBL20548212 | 0.71 | — | — | |
| SCHEMBL14127424 | 0.71 | — | — | |
| SCHEMBL28005723 | 0.71 | — | — | |
| SCHEMBL473650 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 514 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206758-A1 | NAPHTHYRIDINES AS INTEGRIN ANTAGONISTS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2021-07-08 | — | — | US | claimed |
| US-11021493-B2 | 1,4-thiazine dioxide and 1,2,4-thiadiazine dioxide derivatives as beta-secretase inhibitors and methods of use | AMGEN INC. (US) | 2021-06-01 | — | — | US | claimed |
| CN-112142926-A | Curable composition, laminate, and automobile headlamp lens | 三菱化学株式会社 | 2020-12-29 | — | — | CN | claimed |
| US-20200231601-A1 | 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE | AMGEN INC. (US) | 2020-07-23 | — | — | US | claimed |
| EP-3433254-B1 | NAPHTHYRIDINES AS INTEGRIN ANTAGONISTS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-06-17 | — | — | EP | claimed |
| EP-3555086-A1 | 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE | Amgen Inc. (US) | 2019-10-23 | — | — | EP | claimed |
| US-20190112306-A1 | NAPHTHYRIDINES AS INTEGRIN ANTAGONISTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-18 | — | — | US | claimed |
| EP-3433254-A1 | NAPHTHYRIDINES AS INTEGRIN ANTAGONISTS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-01-30 | — | — | EP | claimed |
| WO-2018112094-A1 | 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE | AMGEN INC. (US) | 2018-06-21 | — | — | WO | claimed |
| EP-1600442-B1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | MSD KK (JP) | 2018-01-17 | — | — | EP | claimed |
| EP-1256602-A1 | Dichroic mixture | Rolic AG (CH) | 2002-11-13 | — | — | EP | claimed |
| JP-2001517226-A | — | — | 2001-10-02 | — | — | JP | claimed |
| EP-0971925-A1 | PYRIMIDOPYRIMIDINE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 2000-01-19 | — | — | EP | claimed |
| WO-1998043974-A1 | PYRIMIDOPYRIMIDINE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 1998-10-08 | — | — | WO | claimed |
| US-5073284-A | Phosphonitrilic mixed esters | ETHYL CORPORATION (US) | 1991-12-17 | — | — | US | claimed |
| EP-0118907-B1 | PROCESS FOR FORMING IMAGE | FUJI PHOTO FILM CO., LTD. (JP) | 1987-01-21 | — | — | EP | claimed |
| EP-0197013-A1 | Substituted benzimidazoles for the manufacture of a medicament for treatment of intestinal inflammatory diseases | Aktiebolaget Hässle (SE) | 1986-10-08 | — | — | EP | claimed |
| US-4528258-A | Process for forming image | FUJI PHOTO FILM CO., LTD. (JP) | 1985-07-09 | — | — | US | claimed |
| EP-0120341-A2 | Process for the preparation of pentadienol derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-03 | — | — | EP | claimed |
| EP-0118907-A2 | Process for forming image | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-19 | — | — | EP | claimed |