Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.39 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27174782 | 1.00 | MCHR1 (0.43) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL30804864 | 1.00 | MCHR1 (0.43) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL30665193 | 0.94 | PADI4 (0.43) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL24627778 | 0.94 | PADI4 (0.43) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL27174787 | 0.94 | PADI4 (0.43) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL24627880 | 0.94 | PDE10A (0.40) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL30804861 | 0.94 | KMT2A (0.45) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL24627885 | 0.94 | KMT2A (0.45) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL30804847 | 0.94 | PDE10A (0.40) | MCHR1PADI4PADI2KDM4EALDH1A1 | |
| SCHEMBL27174823 | 0.94 | PDE10A (0.40) | MCHR1PADI4PADI2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148457-A1 | SUBSTITUTED SALICYLAMIDE COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2022-07-14 | — | — | WO | disclosed |