SCHEMBL24628284

SCHEMBL24628284

c1ccc(-c2nc(-c3cccc(-c4ccc5c(c4)c4cccc6sc7cccc5c7c64)c3)nc3c2ccc2ccccc23)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.36
CYP1B1 Q16678 2/20 0.36
CYP1A2 P05177 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ATM Q13315 1/20 0.34
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
RECQL P46063 1/20 0.33
MMP14 P50281 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
WHR1 P49842 1/20 0.33
NQO1 P15559 1/20 0.31
NQO2 P16083 1/20 0.31
MAOA P21397 1/20 0.31
PIK3CA P42336 1/20 0.30
PI4KA P42356 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24628292 0.94 CYP1A1 (0.33) CYP1A1CYP1B1CYP1A2MEN1KMT2A
SCHEMBL22097044 0.93 CYP1A1 (0.36) CYP1A1CYP1B1CYP1A2MEN1KMT2A
SCHEMBL22096948 0.93 CYP1A1 (0.36) CYP1A1CYP1B1CYP1A2MEN1KMT2A
SCHEMBL24628307 0.88 CYP1A1 (0.32) CYP1A1CYP1B1CYP1A2MEN1KMT2A
SCHEMBL24266814 0.88 CYP1A1 (0.37) CYP1A1CYP1B1CYP1A2MEN1KMT2A
SCHEMBL22258632 0.87 MEN1 (0.36) CYP1A1CYP1B1CYP1A2MEN1KMT2A
SCHEMBL24628499 0.86 CYP1A1 (0.38) CYP1A1CYP1B1CYP1A2MEN1KMT2A
SCHEMBL19758443 0.86 MEN1 (0.36) MEN1KMT2AATMWHR1LIMK1
SCHEMBL22880517 0.86 CYP1A1 (0.38) CYP1A1CYP1B1CYP1A2MEN1KMT2A
SCHEMBL24628506 0.86 CYP1A1 (0.34) CYP1A1CYP1B1CYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148717-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 WO disclosed