Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.43 |
| ▸ | HTR2B | P41595 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639001 | 0.79 | HTR2C (0.48) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5631896 | 0.78 | HTR2C (0.48) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5631930 | 0.78 | HTR2C (0.48) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5632683 | 0.78 | HTR2C (0.48) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5633080 | 0.76 | HTR2C (0.49) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5630715 | 0.76 | HTR2C (0.49) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5630722 | 0.76 | HTR2C (0.49) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5632844 | 0.74 | HTR2C (0.50) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5632210 | 0.74 | HTR2C (0.50) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5631197 | 0.74 | HTR2C (0.50) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150461-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2022-07-14 | — | — | WO | disclosed |