Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31225248 | 0.90 | CRBN (0.34) | CASP2NAAAFAAHHPGDENPP2 | |
| SCHEMBL29452140 | 0.89 | LPAR1 (0.46) | CASP2FAAHDNM1ENPP2LPAR1 | |
| SCHEMBL26032382 | 0.88 | LPAR1 (0.48) | CASP2FAAHDNM1ENPP2LPAR1 | |
| SCHEMBL27243701 | 0.88 | LPAR1 (0.48) | CASP2FAAHDNM1ENPP2LPAR1 | |
| SCHEMBL17480750 | 0.88 | LPAR1 (0.48) | CASP2FAAHDNM1ENPP2LPAR1 | |
| SCHEMBL17480732 | 0.88 | LPAR1 (0.48) | CASP2FAAHDNM1ENPP2LPAR1 | |
| SCHEMBL17481272 | 0.88 | LPAR1 (0.48) | CASP2FAAHDNM1ENPP2LPAR1 | |
| SCHEMBL17381386 | 0.88 | LPAR1 (0.48) | CASP2FAAHDNM1ENPP2LPAR1 | |
| SCHEMBL24209427 | 0.87 | LPAR1 (0.47) | CASP2NAAAFAAHDNM1ENPP2 | |
| SCHEMBL24390290 | 0.87 | LPAR1 (0.41) | CASP2NAAAFAAHDNM1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150726-A1 | HYPOIMMUNOGENIC BIOTHERAPEUTICS | OSPREY BIOPHARMACEUTICALS, INC. (US) | 2022-07-14 | — | — | WO | disclosed |