SCHEMBL24630020

SCHEMBL24630020

CCCOCCOCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCNC(=O)CCOCCOCCN=[N+]=[N-])NC(=O)CCCNC(=O)CCOCCOCCC)C(=O)NCCOCCOCCO

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.51
▸ TLR2 O60603 3/20 0.39
▸ NMT2 O60551 1/20 0.37
▸ NMT1 P30419 1/20 0.37
▸ FOLH1 Q04609 3/20 0.37
▸ LPAR3 Q9UBY5 4/20 0.37
▸ LPAR1 Q92633 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29326098 0.96 GLP1R (0.48) GLP1RNMT2NMT1FOLH1
SCHEMBL24630187 0.93 GLP1R (0.55) GLP1RFOLH1
SCHEMBL24630309 0.91 GLP1R (0.56) GLP1RTLR2FOLH1LPAR3
SCHEMBL24630021 0.88 GLP1R (0.52) GLP1RFOLH1
SCHEMBL29727801 0.88 GLP1R (0.52) GLP1RFOLH1
SCHEMBL29727716 0.86 GLP1R (0.54) GLP1RFOLH1
SCHEMBL24629587 0.86 GLP1R (0.54) GLP1RFOLH1
SCHEMBL29326160 0.85 GLP1R (0.46) GLP1RTLR2NMT2NMT1FOLH1
SCHEMBL24630308 0.85 GLP1R (0.47) GLP1RTLR2FOLH1LPAR3LPAR1
SCHEMBL24630070 0.84 GLP1R (0.51) GLP1RFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed
Send feedback