SCHEMBL24630022

SCHEMBL24630022

Cc1c(F)c(F)c(F)c(OC(=O)CCOCCC2CC2CCOCCC2CC2CCNC(=O)[C@H](CCCCNC(=O)CCOCCOCCN=[N+]=[N-])NC(=O)CCCNC(=O)CCOCCOCCN=[N+]=[N-])c1F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.35
▸ ALB P02768 2/20 0.31
▸ FLT1 P17948 1/20 0.31
▸ FLT4 P35916 1/20 0.31
▸ KDR P35968 1/20 0.31
▸ FOLH1 Q04609 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24629998 0.93 GLP1R (0.35) GLP1RALBFLT1FLT4KDR
SCHEMBL24630093 0.91 GLP1R (0.43) GLP1RALBFLT1FLT4KDR
SCHEMBL27391072 0.90 GLP1R (0.42) GLP1RALBFOLH1
SCHEMBL27391075 0.89 GLP1R (0.44) GLP1RALBFLT1FLT4KDR
SCHEMBL24630024 0.88 GLP1R (0.33) GLP1R
SCHEMBL29727780 0.87 GLP1R (0.46) GLP1RALBFOLH1
SCHEMBL24629775 0.87 GLP1R (0.46) GLP1RALBFOLH1
SCHEMBL29329676 0.86 GLP1R (0.47) GLP1RALBFOLH1
SCHEMBL24630197 0.86 GLP1R (0.32) GLP1R
SCHEMBL24629989 0.86 GLP1R (0.44) GLP1RFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed
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