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Sugi Predict / Compounds / SCHEMBL24630315

SCHEMBL24630315

SCHEMBL24630315

[N-]=[N+]=NCCOCCOCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCNC(O)CCOCCOCCN=[N+]=[N-])NC(=O)CCCNC(=O)CCOCCOCCN=[N+]=[N-])C(=O)NCCOCCOCCOCCOCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.42
▸ FOLH1 Q04609 11/20 0.34
▸ TLR2 O60603 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24629989 0.94 GLP1R (0.44) GLP1RFOLH1
SCHEMBL29727767 0.94 GLP1R (0.44) GLP1RFOLH1
SCHEMBL27391844 0.93 GLP1R (0.46) GLP1RFOLH1
SCHEMBL29334288 0.93 GLP1R (0.43) GLP1RFOLH1
SCHEMBL24629775 0.93 GLP1R (0.46) GLP1RFOLH1TLR2
SCHEMBL29727780 0.93 GLP1R (0.46) GLP1RFOLH1TLR2
SCHEMBL29329676 0.92 GLP1R (0.47) GLP1RFOLH1TLR2
SCHEMBL27391072 0.91 GLP1R (0.42) GLP1RFOLH1
SCHEMBL29332260 0.90 GLP1R (0.44) GLP1RFOLH1
SCHEMBL24630308 0.90 GLP1R (0.47) GLP1RFOLH1TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed
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