Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.73 |
| ▸ | CCL2 | P13500 | 2/20 | 0.68 |
| ▸ | TAF1 | P21675 | 1/20 | 0.68 |
| ▸ | BRD2 | P25440 | 1/20 | 0.68 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.68 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.68 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.68 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.68 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.68 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630387 | 0.94 | BRD4 (0.71) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL24630435 | 0.92 | BRD4 (0.83) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL24630488 | 0.92 | BRD4 (0.70) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL24630235 | 0.91 | BRD4 (0.85) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL24630370 | 0.90 | BRD4 (0.72) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL19137924 | 0.85 | BRD4 (1.00) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL19988067 | 0.85 | BRD4 (1.00) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL17477298 | 0.85 | BRD4 (1.00) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL24630424 | 0.84 | BRD4 (0.84) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL19137923 | 0.82 | BRD4 (0.92) | BRD4CCL2TAF1BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150555-A2 | METHODS AND COMPOUNDS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2022-07-14 | — | — | WO | disclosed |