SCHEMBL24633503

SCHEMBL24633503

NS(=O)(=O)c1ccc(N[C@H](CCN2CCCC2)CSc2ccccc2)c(S(=O)(=O)C(F)(F)F)c1

nearest known ligand 0.87

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 15/20 0.87
BCL2 P10415 16/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22879158 1.00 BCL2L1 (0.87) BCL2L1BCL2
SCHEMBL29424547 1.00 BCL2L1 (0.87) BCL2L1BCL2
SCHEMBL30405101 0.99 BCL2L1 (0.85) BCL2L1BCL2
SCHEMBL31570836 0.99 BCL2L1 (0.85) BCL2L1BCL2
SCHEMBL25423836 0.93 BCL2L1 (0.94) BCL2L1BCL2
SCHEMBL25423839 0.93 BCL2L1 (0.94) BCL2L1BCL2
SCHEMBL554094 0.93 BCL2L1 (1.00) BCL2L1BCL2
SCHEMBL554095 0.93 BCL2L1 (1.00) BCL2L1BCL2
SCHEMBL19145119 0.93 BCL2L1 (0.84) BCL2L1BCL2
SCHEMBL30777653 0.93 BCL2L1 (1.00) BCL2L1BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220273666-A1 NANOPARTICLE FORMULATION OF BCL-2 INHIBITOR RECURIUM IP HOLDINGS, LLC 2022-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273666-A1 NANOPARTICLE FORMULATION OF BCL-2 INHIBITOR BCL2, BCL2L2, BCL2L1 BCL2L1 3/4885BCL2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.