Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720500 | 0.88 | DYRK1A (0.35) | HPGDDYRK1AKDM4ENPC1PKM | |
| SCHEMBL24128024 | 0.88 | DYRK1A (0.35) | HPGDDYRK1AKDM4ENPC1PKM | |
| SCHEMBL24128140 | 0.88 | DYRK1A (0.35) | HPGDDYRK1AKDM4ENPC1PKM | |
| SCHEMBL24128091 | 0.87 | DYRK1A (0.34) | HPGDDYRK1A | |
| SCHEMBL24128025 | 0.87 | HPGD (0.44) | HPGDDYRK1ALIMK1KDM4ENPC1 | |
| SCHEMBL24634202 | 0.82 | HPGD (0.32) | HPGDDYRK1A | |
| SCHEMBL24128099 | 0.82 | KDM4E (0.30) | HPGDDYRK1AKDM4E | |
| SCHEMBL30481810 | 0.82 | KDM4E (0.30) | HPGDDYRK1AKDM4E | |
| SCHEMBL24634114 | 0.81 | HPGD (0.33) | HPGDDYRK1A | |
| SCHEMBL24634052 | 0.81 | HPGD (0.33) | HPGDDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022164997-A1 | METHODS FOR THE TREATMENT OF FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2022-08-04 | — | — | WO | disclosed |