SCHEMBL2463518

SCHEMBL2463518

CNC(=O)O.Nc1nccn2c(C3CCCCC3)nc(-c3cccc(OCc4ccccc4)c3)c12

nearest known ligand 0.86

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 20/20 0.86
TNK2 Q07912 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL2464578 0.94 IGF1R (0.93) IGF1R
Carbamic Acid SCHEMBL2460202 0.94 IGF1R (0.92) IGF1R
SCHEMBL2460384 0.93 IGF1R (0.82) IGF1RTNK2
SCHEMBL2460577 0.93 IGF1R (1.00) IGF1RTNK2
SCHEMBL2460396 0.93 IGF1R (1.00) IGF1RTNK2
SCHEMBL2464417 0.92 IGF1R (0.83) IGF1RTNK2
SCHEMBL2463337 0.92 IGF1R (1.00) IGF1RTNK2
SCHEMBL2463556 0.92 IGF1R (0.79) IGF1RTNK2
SCHEMBL2466131 0.91 IGF1R (0.78) IGF1RTNK2
SCHEMBL2460412 0.91 IGF1R (0.78) IGF1RTNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675860-B1 IMIDAZO[1,5-A]PYRAZINES AS TYROSINE KINASE INHIBITORS OSI PHARM INC (US) 2011-09-21 EP claimed