Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.85 |
| ▸ | MEN1 | O00255 | 6/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.85 |
| ▸ | MAPT | P10636 | 5/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.85 |
| ▸ | HPGD | P15428 | 4/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.85 |
| ▸ | DRD2 | P14416 | 2/20 | 0.85 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.85 |
| ▸ | DRD1 | P21728 | 2/20 | 0.85 |
| ▸ | HTR2A | P28223 | 2/20 | 0.85 |
| ▸ | HTR2C | P28335 | 2/20 | 0.85 |
| ▸ | DRD3 | P35462 | 2/20 | 0.85 |
| ▸ | HTR2B | P41595 | 2/20 | 0.85 |
| ▸ | RECQL | P46063 | 2/20 | 0.85 |
| ▸ | HTR6 | P50406 | 2/20 | 0.85 |
| ▸ | CASP1 | P29466 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30027989 | 1.00 | HSD17B10 (0.85) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL30027961 | 1.00 | HSD17B10 (0.85) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL30028419 | 1.00 | HSD17B10 (0.85) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL24635650 | 1.00 | HSD17B10 (0.85) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL30191063 | 1.00 | HSD17B10 (0.85) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL24635619 | 0.94 | HSD17B10 (0.86) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL24635620 | 0.94 | HSD17B10 (0.86) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL7517139 | 0.94 | HSD17B10 (0.86) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL30876124 | 0.94 | HSD17B10 (0.86) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL30886871 | 0.94 | HSD17B10 (0.86) | HSD17B10ALDH1A1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226408-A1 | NOVEL ERGOLINES AND METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2022-10-27 | — | — | WO | disclosed |