Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL28081063 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL2463593 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL5160184 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL1076156 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL29050229 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL5432388 | 0.97 | TDP1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL18278900 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL29050228 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL5195839 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL5432385 | 0.97 | TDP1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613641-A | Efficient phosphorus-free ash water scale inhibition dispersing agent and preparation method thereof | 任丘市昂宇化工有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-116315428-A | Composite diaphragm and preparation method and application thereof | 江苏正力新能电池技术有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-110464803-A | A kind of Chinese medicine composition and preparation method thereof for reducing blood pressure | BY BIOMEDICINE TECH SHENZHEN CO LTD | 2019-11-19 | — | — | CN | claimed |
| CN-110357709-A | A kind of corn resistance physiology slow release fertilizer synergist and the preparation method and application thereof | 中国农业科学院作物科学研究所 | 2019-10-22 | — | — | CN | claimed |
| CN-107266254-A | A kind of fertilizer additive and preparation method thereof | 合肥百绿盛农业科技有限公司 | 2017-10-20 | — | — | CN | claimed |
| CN-106905066-A | A kind of fertilizer additive and preparation method thereof | 温泉县金戈壁农业科技发展有限责任公司 | 2017-06-30 | — | — | CN | claimed |
| CN-106187495-A | A kind of preparation method containing aminoacid Water soluble fertilizer with effect of taking root | 董向波 | 2016-12-07 | — | — | CN | claimed |
| CN-106137950-A | Potassium aspartate pharmaceutical composition and preparation method | 西藏卫信康医药股份有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-103756685-B | A kind of granular saline alkali soil conditioner and production method thereof | INSTITUTE OF AGRICULTURAL RESOURCES AND REGIONAL PLANNING, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2015-11-18 | — | — | CN | claimed |
| CN-105037185-A | Preparation method of potassium aspartate semihydrate | ANHUI WANBANG MEDICAL TECHNOLOGY CO LTD | 2015-11-11 | — | — | CN | claimed |
| CN-104150971-A | Calcium-reinforced SOD urea fertilizer, preparation method and application thereof | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2014-11-19 | — | — | CN | claimed |
| CN-103787796-A | Granular acidic or acidified soil conditioner and preparation method thereof | INST AGRI RESOURCES CAAS | 2014-05-14 | — | — | CN | claimed |
| CN-103787753-A | Compound amino acid fertilizer synergist and preparation method thereof | INST AGRI RESOURCES CAAS | 2014-05-14 | — | — | CN | claimed |
| CN-103787756-A | Polyamino acid fertilizer auxiliary and preparation method for same | INST AGRI RESOURCES CAAS | 2014-05-14 | — | — | CN | claimed |
| CN-103756685-A | Granular saline-alkali soil conditioner and production method thereof | INST AGRI RESOURCES CAAS | 2014-04-30 | — | — | CN | claimed |
| CN-103059299-B | Compound type MSOD (Models of Superoxide Dismutase) and production process thereof | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2014-01-15 | — | — | CN | claimed |
| CN-103059299-A | Compound type MSOD (Models of Superoxide Dismutase) and production process thereof | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2013-04-24 | — | — | CN | claimed |
| CN-102875403-A | Method for preparing potassium L-aspartate | YIXING QIANCHENG BIOLOG CO LTD | 2013-01-16 | — | — | CN | claimed |
| CN-1087598-C | Gourmet powder | XUE YONG (CN) | 2002-07-17 | — | — | CN | claimed |
| CN-1181898-A | Gourmet powder | XIE YONG (CN) | 1998-05-20 | — | — | CN | claimed |