Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800275 | 0.83 | GLA (0.54) | GLASCN8ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24637978 | 0.81 | GLA (0.55) | GLASCN8AFFAR1IDH1FFAR4 | |
| SCHEMBL24637999 | 0.79 | GLA (0.49) | GLASCN8AFFAR1IDH1FFAR4 | |
| SCHEMBL2154019 | 0.78 | GLA (0.53) | GLAFFAR1FFAR4MRGPRX4MAOB | |
| SCHEMBL19407048 | 0.78 | GLA (0.55) | GLASCN8ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11929201 | 0.76 | TAAR1 (0.53) | MAOBHRH3ALDH1A1 | |
| SCHEMBL4934435 | 0.75 | GLA (0.51) | GLASCN8AFFAR1IDH1FFAR4 | |
| SCHEMBL17784702 | 0.75 | GLA (0.49) | GLASCN8AFFAR1IDH1FFAR4 | |
| SCHEMBL28865565 | 0.75 | HTR2B (0.50) | GLASCN8AFFAR1FFAR4MRGPRX4 | |
| SCHEMBL28248372 | 0.75 | HTR2B (0.54) | GLASCN8AFFAR1FFAR4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192598-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-09-15 | — | — | WO | disclosed |