Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24638517 | 0.83 | SCD (0.34) | RETSCDIRAK4KDM4AKDM4B | |
| SCHEMBL24638053 | 0.76 | KDM4A (0.44) | RETSCDIRAK4KDM4AKDM4B | |
| SCHEMBL24638274 | 0.72 | KDM4A (0.41) | RETSCDIRAK4KDM4AKDM4B | |
| SCHEMBL23610887 | 0.69 | BCL6 (0.41) | RETSCDIRAK4KDM4AKDM4B | |
| SCHEMBL20177023 | 0.67 | KCNJ1 (0.50) | IRAK4 | |
| SCHEMBL16649172 | 0.64 | SCD (0.47) | RETSCDIRAK4KDM4AKDM4B | |
| SCHEMBL24342581 | 0.64 | KDM4A (0.38) | SCDIRAK4KDM4AKDM4BKDM5C | |
| SCHEMBL7349175 | 0.63 | MAPK1 (0.36) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL16867187 | 0.63 | GAA (0.55) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL31517442 | 0.63 | PDE10A (0.36) | SCDBCL6PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022231242-A1 | INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY | 주식회사 스탠다임 | 2022-11-03 | — | — | WO | disclosed |