SCHEMBL24638522

SCHEMBL24638522

c1ccc(-c2ccc(N(c3ccccc3)c3ccc4cc(-c5ccc6c(-c7ccccc7)c(-c7ccccc7)c(-c7ccccc7)c(-c7ccccc7)c6c5)ccc4c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.42
ESR2 Q92731 4/20 0.42
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
HSD17B1 P14061 2/20 0.38
HSD17B2 P37059 2/20 0.38
CYP2B6 P20813 1/20 0.38
BACE1 P56817 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
NPC1 O15118 1/20 0.35
CDK4 P11802 2/20 0.33
CCND1 P24385 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24638523 0.98 ESR1 (0.40) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL26337410 0.94 ESR1 (0.40) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL26339891 0.94 ESR1 (0.42) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL24638544 0.94 ESR1 (0.42) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL26337511 0.93 ESR1 (0.38) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL26337405 0.93 ESR1 (0.38) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL26339921 0.93 ESR1 (0.38) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL26339893 0.93 ESR1 (0.38) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL26337505 0.93 ESR1 (0.38) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL13158749 0.93 ESR1 (0.41) ESR1ESR2CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11417843-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2022-08-16 US disclosed