Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 17/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24639389 | 1.00 | TIPARP (0.49) | TIPARPPARP2SOS1OGACHRM2 | |
| SCHEMBL24639355 | 1.00 | TIPARP (0.49) | TIPARPPARP2SOS1OGACHRM2 | |
| SCHEMBL26959648 | 0.89 | TIPARP (0.48) | TIPARPPARP2SOS1 | |
| SCHEMBL24640244 | 0.89 | TIPARP (0.48) | TIPARPPARP2SOS1 | |
| SCHEMBL24640309 | 0.89 | TIPARP (0.48) | TIPARPPARP2SOS1 | |
| SCHEMBL26958101 | 0.86 | TIPARP (0.47) | TIPARPPARP2HTR2B | |
| SCHEMBL24640620 | 0.86 | TIPARP (0.47) | TIPARPPARP2HTR2B | |
| SCHEMBL24639358 | 0.84 | SOS1 (0.41) | TIPARPPARP2SOS1 | |
| SCHEMBL24639353 | 0.84 | SOS1 (0.41) | TIPARPPARP2SOS1 | |
| SCHEMBL24954331 | 0.83 | TIPARP (0.45) | TIPARPPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |