Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321073 | 0.87 | PPARD (0.53) | CYP1A1CYP1B1PPARDPPARAPPARG | |
| SCHEMBL4321078 | 0.87 | PPARD (0.53) | CYP1A1CYP1B1PPARDPPARAPPARG | |
| SCHEMBL28868239 | 0.87 | PPARD (0.39) | CYP1A1CYP1B1PPARDPPARAPPARG | |
| SCHEMBL30003645 | 0.85 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL1765829 | 0.84 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL12648504 | 0.84 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL12732422 | 0.84 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL2463761 | 0.84 | PPARA (0.54) | PPARDPPARAPPARG | |
| SCHEMBL2464436 | 0.84 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL12648327 | 0.84 | PPARA (0.54) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |
| US-7652045-B2 | e.g. [[7-Allyl-3-[2-[2-(2,4-dichlorophenyl)-5-isopropyl-4-oxazolyl]ethyl]-1,2-benzisoxazol-6-yl]oxy]acetic acid; with vehicles (lactose, D-mannitol, glucose), disintegrators (starch or carboxymethylcellulose calcium ), binders (hydroxypropylcellulose) and lubricants (magnesium stearate or talc) | NIPPON CHEMIPHAR, CO., LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7648999-B2 | Activator for peroxisome proliferator-activated receptor δ | NIPPON CHEMIPHAR CO., LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| US-20080009525-A1 | Activator of peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2008-01-10 | — | — | US | disclosed |
| US-20080009631-A1 | Activator for peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2008-01-10 | — | — | US | disclosed |
| US-7265137-B2 | Activator of peroxisome proliferator-activated re-ceptor δ | NIPPON CHEMIPHAR CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-20050054674-A1 | Activator of peroxisome proliferator-activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-03-10 | — | — | US | disclosed |
| EP-1424330-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009525-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARG, PPARD, PPARA | CYP1A1 308/4885CYP1B1 574/4885CXCL12 2617/4885 |
| US-20080009631-A1 | Activator for peroxisome proliferator-activated receptor delta | PPARG, PPARD, PPARA | CYP1A1 352/4885CYP1B1 616/4885CXCL12 2584/4885 |
| US-20050054674-A1 | Activator of peroxisome proliferator-activated receptor | PPARG, PPARD, PPARA | CYP1A1 368/4885CYP1B1 716/4885CXCL12 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.