Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.44 |
| ▸ | HTR2C | P28335 | 20/20 | 0.44 |
| ▸ | HTR2B | P41595 | 19/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244833 | 0.85 | HTR2A (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244682 | 0.85 | HTR2A (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244790 | 0.85 | HTR2A (0.45) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244633 | 0.85 | HTR2A (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244674 | 0.85 | HTR2A (0.45) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244610 | 0.85 | HTR2A (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244809 | 0.85 | HTR2A (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244792 | 0.85 | HTR2A (0.45) | HTR2AHTR2CHTR2B | |
| SCHEMBL31245111 | 0.83 | HTR2C (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244984 | 0.83 | HTR2C (0.44) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |