Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.40 |
| ▸ | HTR2B | P41595 | 17/20 | 0.40 |
| ▸ | HTR2A | P28223 | 17/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244707 | 0.81 | HTR2C (0.44) | HTR2CHTR2BHTR2A | |
| SCHEMBL31244769 | 0.81 | HTR2C (0.44) | HTR2CHTR2BHTR2A | |
| SCHEMBL29841889 | 0.76 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL24675511 | 0.76 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL24763593 | 0.76 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL24675301 | 0.75 | TIPARP (0.42) | HTR2CHTR2BHTR2A | |
| SCHEMBL14465882 | 0.75 | TIPARP (0.42) | HTR2CHTR2BHTR2A | |
| SCHEMBL24675309 | 0.75 | TIPARP (0.42) | HTR2CHTR2BHTR2A | |
| SCHEMBL30104829 | 0.75 | TIPARP (0.42) | HTR2CHTR2BHTR2A | |
| SCHEMBL31244787 | 0.74 | HTR2C (0.49) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |