Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 5/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 3/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24639973 | 1.00 | TIPARP (0.39) | TIPARPSOS1KRASRPS6KA1HTR2A | |
| SCHEMBL24639257 | 1.00 | TIPARP (0.39) | TIPARPSOS1KRASRPS6KA1HTR2A | |
| SCHEMBL24640214 | 0.91 | TIPARP (0.34) | TIPARPSOS1KRASIDH1 | |
| SCHEMBL24640712 | 0.91 | TIPARP (0.34) | TIPARPSOS1KRASIDH1 | |
| SCHEMBL24640213 | 0.91 | TIPARP (0.34) | TIPARPSOS1KRASIDH1 | |
| SCHEMBL24639252 | 0.90 | TIPARP (0.38) | TIPARPSOS1KRAS | |
| SCHEMBL24639282 | 0.89 | TIPARP (0.38) | TIPARPSOS1KRAS | |
| SCHEMBL24639392 | 0.89 | TIPARP (0.38) | TIPARPSOS1KRAS | |
| SCHEMBL24639382 | 0.89 | TIPARP (0.38) | TIPARPSOS1KRAS | |
| SCHEMBL24639988 | 0.88 | SOS1 (0.39) | TIPARPSOS1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |