Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640628 | 0.88 | TIPARP (0.35) | TIPARPEIF2AK4KRAS | |
| SCHEMBL24639252 | 0.82 | TIPARP (0.38) | TIPARPKRAS | |
| SCHEMBL31245400 | 0.78 | HTR2A (0.51) | — | |
| SCHEMBL31244776 | 0.78 | HTR2A (0.51) | — | |
| SCHEMBL31245068 | 0.78 | HTR2A (0.51) | — | |
| SCHEMBL24640634 | 0.74 | TIPARP (0.36) | TIPARPEIF2AK4KRAS | |
| SCHEMBL24639973 | 0.71 | TIPARP (0.39) | TIPARPKRAS | |
| SCHEMBL24639257 | 0.71 | TIPARP (0.39) | TIPARPKRAS | |
| SCHEMBL24639282 | 0.71 | TIPARP (0.38) | TIPARPKRAS | |
| SCHEMBL24639392 | 0.71 | TIPARP (0.38) | TIPARPKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |