Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640705 | 0.82 | HRH3 (0.35) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL24640241 | 0.82 | HRH3 (0.35) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL24640698 | 0.78 | — | — | |
| SCHEMBL24639519 | 0.76 | KRAS (0.39) | — | |
| SCHEMBL24639546 | 0.76 | KRAS (0.39) | — | |
| SCHEMBL24639545 | 0.76 | KRAS (0.39) | — | |
| SCHEMBL24640453 | 0.76 | MDM2 (0.42) | KDM4EKCNH2 | |
| SCHEMBL24640467 | 0.76 | MDM2 (0.42) | KDM4EKCNH2 | |
| SCHEMBL24640462 | 0.76 | MDM2 (0.42) | KDM4EKCNH2 | |
| SCHEMBL31244610 | 0.75 | HTR2A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |