Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 7/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24639326 | 1.00 | TIPARP (0.51) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24639329 | 1.00 | TIPARP (0.51) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24640409 | 0.92 | TIPARP (0.49) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24640747 | 0.86 | TIPARP (0.40) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24639999 | 0.85 | TIPARP (0.48) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24640010 | 0.85 | TIPARP (0.48) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24639327 | 0.83 | TIPARP (0.41) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24639351 | 0.83 | TIPARP (0.41) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24640736 | 0.83 | TIPARP (0.41) | TIPARPHRH3ALDH1A1LMNAHTT | |
| SCHEMBL24639983 | 0.82 | TIPARP (0.38) | TIPARPHRH3ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |